Cyclogest also known as Progesterone (Proh-jest-er-rone) is a hormone which occurs naturally in the body. It helps relieve the symptoms associated with progesterone deficiencies like post-natal depression and premenstrual syndrome. The pessary may be inserted into the vagina or back passage. Use Cyclogest rectally if barrier methods of contraception are used or if you are suffering from vaginal infection or cystitis. Use Cyclogest vaginally if you suffer from colitis or faecal incontinence once the pessary has dissolved. Progesterone is absorbed into the body.